Trichodermin Induces G0/G1 Cell Cycle Arrest by Inhibiting c-Myc in Ovarian Cancer Cells and Tumor Xenograft-Bearing Mice

Ovarian cancer is a fatal gynecological cancer because of a lack of early diagnosis, which often relapses as chemoresistant. Trichodermin, a trichothecene first isolated from Trichoderma viride, is an inhibitor of eukaryotic protein synthesis. However, whether trichodermin is able to suppress ovaria...

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Detalles Bibliográficos
Autores principales: Gao, Ying, Miles, Sarah L., Dasgupta, Piyali, Rankin, Gary O., Cutler, Stephen, Chen, Yi Charlie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8126000/
https://www.ncbi.nlm.nih.gov/pubmed/34065149
http://dx.doi.org/10.3390/ijms22095022

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8126000/
https://www.ncbi.nlm.nih.gov/pubmed/34065149
http://dx.doi.org/10.3390/ijms22095022

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