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Trichodermin Induces G0/G1 Cell Cycle Arrest by Inhibiting c-Myc in Ovarian Cancer Cells and Tumor Xenograft-Bearing Mice
Ovarian cancer is a fatal gynecological cancer because of a lack of early diagnosis, which often relapses as chemoresistant. Trichodermin, a trichothecene first isolated from Trichoderma viride, is an inhibitor of eukaryotic protein synthesis. However, whether trichodermin is able to suppress ovaria...
Autores principales: | Gao, Ying, Miles, Sarah L., Dasgupta, Piyali, Rankin, Gary O., Cutler, Stephen, Chen, Yi Charlie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8126000/ https://www.ncbi.nlm.nih.gov/pubmed/34065149 http://dx.doi.org/10.3390/ijms22095022 |
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