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KCNK3 Mutation Causes Altered Immune Function in Pulmonary Arterial Hypertension Patients and Mouse Models

Loss of function KCNK3 mutation is one of the gene variants driving hereditary pulmonary arterial hypertension (PAH). KCNK3 is expressed in several cell and tissue types on both membrane and endoplasmic reticulum and potentially plays a role in multiple pathological process associated with PAH. Howe...

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Detalles Bibliográficos
Autores principales: West, James D., Austin, Eric D., Rizzi, Elise M., Yan, Ling, Tanjore, Harikrishna, Crabtree, Amber L., Moore, Christy S., Muthian, Gladson, Carrier, Erica J., Jacobson, David A., Hamid, Rizwan, Kendall, Peggy L., Majka, Susan, Rathinasabapathy, Anandharajan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8126011/
https://www.ncbi.nlm.nih.gov/pubmed/34065088
http://dx.doi.org/10.3390/ijms22095014