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Targeting SIRT2 Sensitizes Melanoma Cells to Cisplatin via an EGFR-Dependent Mechanism

Melanoma cells are resistant to most anticancer chemotherapeutics. Despite poor response rates and short-term efficacy, chemotherapy remains the main approach to treating this cancer. The underlying mechanisms of the intrinsic chemoresistance of melanoma remain unclear, but elucidating these mechani...

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Detalles Bibliográficos
Autores principales: Karwaciak, Iwona, Sałkowska, Anna, Karaś, Kaja, Dastych, Jarosław, Ratajewski, Marcin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8126047/
https://www.ncbi.nlm.nih.gov/pubmed/34068624
http://dx.doi.org/10.3390/ijms22095034