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Targeting SIRT2 Sensitizes Melanoma Cells to Cisplatin via an EGFR-Dependent Mechanism
Melanoma cells are resistant to most anticancer chemotherapeutics. Despite poor response rates and short-term efficacy, chemotherapy remains the main approach to treating this cancer. The underlying mechanisms of the intrinsic chemoresistance of melanoma remain unclear, but elucidating these mechani...
Autores principales: | Karwaciak, Iwona, Sałkowska, Anna, Karaś, Kaja, Dastych, Jarosław, Ratajewski, Marcin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8126047/ https://www.ncbi.nlm.nih.gov/pubmed/34068624 http://dx.doi.org/10.3390/ijms22095034 |
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