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α-Trifluoromethyl Chalcones as Potent Anticancer Agents for Androgen Receptor-Independent Prostate Cancer

α-Trifluoromethyl chalcones were prepared and evaluated for their antiproliferative activities against androgen-independent prostate cancer cell lines as well as five additional types of human tumor cell lines. The most potent chalcone 5 showed superior antitumor activity in vivo with both oral and...

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Detalles Bibliográficos
Autores principales: Saito, Yohei, Mizokami, Atsushi, Izumi, Kouji, Naito, Renato, Goto, Masuo, Nakagawa-Goto, Kyoko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8126091/
https://www.ncbi.nlm.nih.gov/pubmed/34068627
http://dx.doi.org/10.3390/molecules26092812