Impact of uORFs in mediating regulation of translation in stress conditions

BACKGROUND: A large fraction of genes contains upstream ORFs (uORFs) in the 5′ untranslated region (5’UTR). The translation of uORFs can inhibit the translation of the main coding sequence, for example by causing premature dissociation of the two ribosomal units or ribosome stalling. However, it is...

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Detalles Bibliográficos
Autores principales: Moro, Simone G., Hermans, Cedric, Ruiz-Orera, Jorge, Albà, M. Mar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8126119/
https://www.ncbi.nlm.nih.gov/pubmed/33992089
http://dx.doi.org/10.1186/s12860-021-00363-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8126119/
https://www.ncbi.nlm.nih.gov/pubmed/33992089
http://dx.doi.org/10.1186/s12860-021-00363-9

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