ID1 mediates resistance to osimertinib in EGFR T790M-positive non-small cell lung cancer through epithelial–mesenchymal transition

BACKGROUND: ID1 is associated with resistance to the first generation of EGFR tyrosine kinase inhibitors (EGFR-TKIs) in non-small cell lung cancer (NSCLC). However, the effect of ID1 expression on osimertinib resistance in EGFR T790M-positive NSCLC is not clear. METHODS: We established a drug-resist...

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Detalles Bibliográficos
Autores principales: Liu, Kejun, Chen, Xianwen, Wu, Ligang, Chen, Shiyuan, Fang, Nianxin, Cai, Limin, Jia, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8126145/
https://www.ncbi.nlm.nih.gov/pubmed/33992097
http://dx.doi.org/10.1186/s12890-021-01540-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8126145/
https://www.ncbi.nlm.nih.gov/pubmed/33992097
http://dx.doi.org/10.1186/s12890-021-01540-4

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