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High-fat diet impairs duodenal barrier function and elicits glia-dependent changes along the gut-brain axis that are required for anxiogenic and depressive-like behaviors

BACKGROUND: Mood and metabolic disorders are interrelated and may share common pathological processes. Autonomic neurons link the brain with the gastrointestinal tract and constitute a likely pathway for peripheral metabolic challenges to affect behaviors controlled by the brain. The activities of n...

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Detalles Bibliográficos
Autores principales: Seguella, Luisa, Pesce, Mirella, Capuano, Riccardo, Casano, Fabrizio, Pesce, Marcella, Corpetti, Chiara, Vincenzi, Martina, Maftei, Daniela, Lattanzi, Roberta, Del Re, Alessandro, Sarnelli, Giovanni, Gulbransen, Brian D., Esposito, Giuseppe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8126158/
https://www.ncbi.nlm.nih.gov/pubmed/33993886
http://dx.doi.org/10.1186/s12974-021-02164-5