Cargando…

High-fat diet impairs duodenal barrier function and elicits glia-dependent changes along the gut-brain axis that are required for anxiogenic and depressive-like behaviors

BACKGROUND: Mood and metabolic disorders are interrelated and may share common pathological processes. Autonomic neurons link the brain with the gastrointestinal tract and constitute a likely pathway for peripheral metabolic challenges to affect behaviors controlled by the brain. The activities of n...

Descripción completa

Detalles Bibliográficos
Autores principales:	Seguella, Luisa, Pesce, Mirella, Capuano, Riccardo, Casano, Fabrizio, Pesce, Marcella, Corpetti, Chiara, Vincenzi, Martina, Maftei, Daniela, Lattanzi, Roberta, Del Re, Alessandro, Sarnelli, Giovanni, Gulbransen, Brian D., Esposito, Giuseppe
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8126158/ https://www.ncbi.nlm.nih.gov/pubmed/33993886 http://dx.doi.org/10.1186/s12974-021-02164-5

Ejemplares similares

A Palmitoylethanolamide Producing Lactobacillus paracasei Improves Clostridium difficile Toxin A-Induced Colitis
por: Esposito, Giuseppe, et al.
Publicado: (2021)

The potential of cannabidiol in the COVID‐19 pandemic
por: Esposito, Giuseppe, et al.
Publicado: (2020)

S100B Protein Stimulates Proliferation and Angiogenic Mediators Release through RAGE/pAkt/mTOR Pathway in Human Colon Adenocarcinoma Caco-2 Cells
por: Seguella, Luisa, et al.
Publicado: (2019)

Oral Adelmidrol Administration Up-Regulates Palmitoylethanolamide Production in Mice Colon and Duodenum through a PPAR-γ Independent Action
por: Del Re, Alessandro, et al.
Publicado: (2022)

HIV-1 Tat-induced diarrhea is improved by the PPARalpha agonist, palmitoylethanolamide, by suppressing the activation of enteric glia
por: Sarnelli, Giovanni, et al.
Publicado: (2018)

Role of Enteric Glia as Bridging Element between Gut Inflammation and Visceral Pain Consolidation during Acute Colitis in Rats
por: Lucarini, Elena, et al.
Publicado: (2021)

Cannabidiol inhibits SARS‐Cov‐2 spike (S) protein‐induced cytotoxicity and inflammation through a PPARγ‐dependent TLR4/NLRP3/Caspase‐1 signaling suppression in Caco‐2 cell line
por: Corpetti, Chiara, et al.
Publicado: (2021)

Next-Generation Probiotics for Inflammatory Bowel Disease
por: Pesce, Marcella, et al.
Publicado: (2022)

Pentamidine niosomes thwart S100B effects in human colon carcinoma biopsies favouring wtp53 rescue
por: Seguella, Luisa, et al.
Publicado: (2020)

Ultramicronized Palmitoylethanolamide Inhibits NLRP3 Inflammasome Expression and Pro-Inflammatory Response Activated by SARS-CoV-2 Spike Protein in Cultured Murine Alveolar Macrophages
por: Del Re, Alessandro, et al.
Publicado: (2021)

N-Palmitoyl-D-Glucosamine Inhibits TLR-4/NLRP3 and Improves DNBS-Induced Colon Inflammation through a PPAR-α-Dependent Mechanism
por: Palenca, Irene, et al.
Publicado: (2022)

Engineered Lactobacillus paracasei Producing Palmitoylethanolamide (PEA) Prevents Colitis in Mice
por: Esposito, Giuseppe, et al.
Publicado: (2021)

Nutraceuticals and Diet Supplements in Crohn’s Disease: A General Overview of the Most Promising Approaches in the Clinic
por: De Conno, Barbara, et al.
Publicado: (2022)

Impaired Duodenal Palmitoylethanolamide Release Underlies Acid-Induced Mast Cell Activation in Functional Dyspepsia
por: Sarnelli, Giovanni, et al.
Publicado: (2020)

Leaky gut, dysbiosis, and enteric glia activation: the trilogy behind the intestinal origin of Parkinson’s disease
por: Seguella, Luisa, et al.
Publicado: (2019)

Can the enteric nervous system be an alternative entrance door in SARS-CoV2 neuroinvasion?
por: Esposito, Giuseppe, et al.
Publicado: (2020)

HIV-1 Tat-induced diarrhea evokes an enteric glia-dependent neuroinflammatory response in the central nervous system
por: Esposito, Giuseppe, et al.
Publicado: (2017)

Circuit-specific enteric glia regulate intestinal motor neurocircuits
por: Ahmadzai, Mohammad M., et al.
Publicado: (2021)

Oral Immunization with Escherichia coli Nissle 1917 Expressing SARS-CoV-2 Spike Protein Induces Mucosal and Systemic Antibody Responses in Mice
por: Sarnelli, Giovanni, et al.
Publicado: (2023)

Autologous transplantation of intestine-isolated glia cells improves neuropathology and restores cognitive deficits in β amyloid-induced neurodegeneration
por: Esposito, Giuseppe, et al.
Publicado: (2016)

Endocannabinoid‐related compounds in gastrointestinal diseases
por: Pesce, Marcella, et al.
Publicado: (2017)

Rifaximin Improves Clostridium difficile Toxin A-Induced Toxicity in Caco-2 Cells by the PXR-Dependent TLR4/MyD88/NF-κB Pathway
por: Esposito, Giuseppe, et al.
Publicado: (2016)

Sleeve Gastrectomy-Induced Body Mass Index Reduction Increases the Intensity of Taste Perception’s and Reduces Bitter-Induced Pleasantness in Severe Obesity
por: Rurgo, Sara, et al.
Publicado: (2022)

Modern Achalasia: Diagnosis, Classification, and Treatment
por: Pesce, Marcella, et al.
Publicado: (2023)

Involvement of dynorphin in anxiogenic effects of estrogen
por: Kastenberger, Iris, et al.
Publicado: (2009)

Enteric Glia: A New Player in Abdominal Pain
por: Morales-Soto, Wilmarie, et al.
Publicado: (2018)

Palmitoylethanolamide Modulates Inflammation-Associated Vascular Endothelial Growth Factor (VEGF) Signaling via the Akt/mTOR Pathway in a Selective Peroxisome Proliferator-Activated Receptor Alpha (PPAR-α)-Dependent Manner
por: Sarnelli, Giovanni, et al.
Publicado: (2016)

Paradoxical anxiogenic response of juvenile mice to fluoxetine
por: Oh, Ji-eun, et al.
Publicado: (2009)

Oxytocin-induced anxiogenic behavior in juvenile male rats
por: Jang, Minji, et al.
Publicado: (2021)

Febrile Seizures Cause Depression and Anxiogenic Behaviors in Rats
por: Yu, Yeon Hee, et al.
Publicado: (2022)

Evaluation of reflux following sleeve gastrectomy and one anastomosis gastric bypass: 1-year results from a randomized open-label controlled trial
por: Musella, Mario, et al.
Publicado: (2020)

Astrocyte Cell Surface Antigen 2 and Other Potential Cell Surface Markers of Enteric glia in the Mouse Colon
por: Grubišić, Vladimir, et al.
Publicado: (2022)

Enteric Glia Regulate Lymphocyte Activation via Autophagy-Mediated MHC-II Expression
por: Chow, Aaron K., et al.
Publicado: (2021)

N-Acetylcysteine Protects against the Anxiogenic Response to Cisplatin in Rats
por: Vukovic, Rade, et al.
Publicado: (2019)

Trait Anxiety Does Not Predict the Anxiogenic Response to Sleep Deprivation
por: Sundelin, Tina, et al.
Publicado: (2022)

Identification and Characterization of a New Splicing Variant of Prokineticin 2
por: Lattanzi, Roberta, et al.
Publicado: (2022)

Identification of Regions Involved in the Physical Interaction between Melanocortin Receptor Accessory Protein 2 and Prokineticin Receptor 2
por: Fullone, Maria Rosaria, et al.
Publicado: (2022)

Arginine 125 Is an Essential Residue for the Function of MRAP2
por: Fullone, Maria Rosaria, et al.
Publicado: (2022)

NPFFR2 Activates the HPA Axis and Induces Anxiogenic Effects in Rodents
por: Lin, Ya-Tin, et al.
Publicado: (2017)

Firing patterns of ventral hippocampal neurons predict the exploration of anxiogenic locations
por: Malagon-Vina, Hugo, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_bda3rca4q8ilo9he3rba3rtvrm