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PEPPRO: quality control and processing of nascent RNA profiling data

Nascent RNA profiling is growing in popularity; however, there is no standard analysis pipeline to uniformly process the data and assess quality. Here, we introduce PEPPRO, a comprehensive, scalable workflow for GRO-seq, PRO-seq, and ChRO-seq data. PEPPRO produces uniformly processed output files fo...

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Detalles Bibliográficos
Autores principales: Smith, Jason P., Dutta, Arun B., Sathyan, Kizhakke Mattada, Guertin, Michael J., Sheffield, Nathan C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8126160/
https://www.ncbi.nlm.nih.gov/pubmed/33992117
http://dx.doi.org/10.1186/s13059-021-02349-4