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INPP5E controls ciliary localization of phospholipids and the odor response in olfactory sensory neurons

The lipid composition of the primary cilia membrane is emerging as a critical regulator of cilia formation, maintenance and function. Here, we show that conditional deletion of the phosphoinositide 5′-phosphatase gene Inpp5e, mutation of which is causative of Joubert syndrome, in terminally develope...

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Detalles Bibliográficos
Autores principales: Ukhanov, Kirill, Uytingco, Cedric, Green, Warren, Zhang, Lian, Schurmans, Stephane, Martens, Jeffrey R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8126451/
https://www.ncbi.nlm.nih.gov/pubmed/33771931
http://dx.doi.org/10.1242/jcs.258364