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(Dis)Solving the problem of aberrant protein states

Neurodegenerative diseases and other protein-misfolding disorders represent a longstanding biomedical challenge, and effective therapies remain largely elusive. This failure is due, in part, to the recalcitrant and diverse nature of misfolded protein conformers. Recent work has uncovered that many a...

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Detalles Bibliográficos
Autores principales: Fare, Charlotte M., Shorter, James
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8126477/
https://www.ncbi.nlm.nih.gov/pubmed/33942880
http://dx.doi.org/10.1242/dmm.048983