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The effect of targeting Tie2 on hemorrhagic shock-induced renal perfusion disturbances in rats

BACKGROUND: Hemorrhagic shock is associated with acute kidney injury and increased mortality. Targeting the endothelial angiopoietin/Tie2 system, which regulates endothelial permeability, previously reduced hemorrhagic shock-induced vascular leakage. We hypothesized that as a consequence of vascular...

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Detalles Bibliográficos
Autores principales: van Leeuwen, Anoek L. I., Dekker, Nicole A. M., Van Slyke, Paul, de Groot, Esther, Vervloet, Marc G., Roelofs, Joris J. T. H., van Meurs, Matijs, van den Brom, Charissa E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8126531/
https://www.ncbi.nlm.nih.gov/pubmed/33997943
http://dx.doi.org/10.1186/s40635-021-00389-5