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Naturally Occurring Genetic Alterations in Proximal TCR Signaling and Implications for Cancer Immunotherapy

T cell-based immunotherapies including genetically engineered T cells, adoptive transfer of tumor-infiltrating lymphocytes, and immune checkpoint blockade highlight the impressive anti-tumor effects of T cells. These successes have provided new hope to many cancer patients with otherwise poor progno...

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Detalles Bibliográficos
Autores principales: Kent, Andrew, Longino, Natalie V., Christians, Allison, Davila, Eduardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8126620/
https://www.ncbi.nlm.nih.gov/pubmed/34012443
http://dx.doi.org/10.3389/fimmu.2021.658611