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Identification of Potential Binders of Mtb Universal Stress Protein (Rv1636) Through an in silico Approach and Insights Into Compound Selection for Experimental Validation

Millions of deaths caused by Mycobacterium tuberculosis (Mtb) are reported worldwide every year. Treatment of tuberculosis (TB) involves the use of multiple antibiotics over a prolonged period. However, the emergence of resistance leading to multidrug-resistant TB (MDR-TB) and extensively drug-resis...

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Detalles Bibliográficos
Autores principales: Chakraborti, Sohini, Chakraborty, Moubani, Bose, Avipsa, Srinivasan, Narayanaswamy, Visweswariah, Sandhya S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8126637/
https://www.ncbi.nlm.nih.gov/pubmed/34012976
http://dx.doi.org/10.3389/fmolb.2021.599221