Plasmodium falciparum LipB mutants display altered redox and carbon metabolism in asexual stages and cannot complete sporogony in Anopheles mosquitoes

Malaria is still one of the most important global infectious diseases. Emergence of drug resistance and a shortage of new efficient antimalarials continue to hamper a malaria eradication agenda. Malaria parasites are highly sensitive to changes in the redox environment. Understanding the mechanisms...

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Detalles Bibliográficos
Autores principales: Biddau, Marco, Santha Kumar, T.R., Henrich, Philipp, Laine, Larissa M., Blackburn, Gavin J., Chokkathukalam, Achuthanunni, Li, Tao, Lee Sim, Kim, King, Lewis, Hoffman, Stephen L., Barrett, Michael P., Coombs, Graham H., McFadden, Geoffrey I., Fidock, David A., Müller, Sylke, Sheiner, Lilach
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8126644/
https://www.ncbi.nlm.nih.gov/pubmed/33713652
http://dx.doi.org/10.1016/j.ijpara.2020.10.011

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8126644/
https://www.ncbi.nlm.nih.gov/pubmed/33713652
http://dx.doi.org/10.1016/j.ijpara.2020.10.011

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