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Evaluating DNA Methylation, Gene Expression, Somatic Mutation, and Their Combinations in Inferring Tumor Tissue-of-Origin

Carcinoma of unknown primary (CUP) is a type of metastatic cancer, the primary tumor site of which cannot be identified. CUP occupies approximately 5% of cancer incidences in the United States with usually unfavorable prognosis, making it a big threat to public health. Traditional methods to identif...

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Detalles Bibliográficos
Autores principales: Liu, Haiyan, Qiu, Chun, Wang, Bo, Bing, Pingping, Tian, Geng, Zhang, Xueliang, Ma, Jun, He, Bingsheng, Yang, Jialiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8126648/
https://www.ncbi.nlm.nih.gov/pubmed/34012960
http://dx.doi.org/10.3389/fcell.2021.619330