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Evaluating DNA Methylation, Gene Expression, Somatic Mutation, and Their Combinations in Inferring Tumor Tissue-of-Origin
Carcinoma of unknown primary (CUP) is a type of metastatic cancer, the primary tumor site of which cannot be identified. CUP occupies approximately 5% of cancer incidences in the United States with usually unfavorable prognosis, making it a big threat to public health. Traditional methods to identif...
Autores principales: | Liu, Haiyan, Qiu, Chun, Wang, Bo, Bing, Pingping, Tian, Geng, Zhang, Xueliang, Ma, Jun, He, Bingsheng, Yang, Jialiang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8126648/ https://www.ncbi.nlm.nih.gov/pubmed/34012960 http://dx.doi.org/10.3389/fcell.2021.619330 |
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