Neonatal T Helper 17 Responses Are Skewed Towards an Immunoregulatory Interleukin-22 Phenotype

Newborns are frequently affected by mucocutaneous candidiasis. Th17 cells essentially limit mucosal invasion by commensal Candida spp. Here, we sought to understand the molecular basis for the developmental lack of Th17 cell responses in circulating blood neonatal T cells. Naive cord blood CD4 T cel...

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Detalles Bibliográficos
Autores principales: Razzaghian, Hamid R., Sharafian, Zohreh, Sharma, Ashish A., Boyce, Guilaine K., Lee, Kelsey, Da Silva, Rachel, Orban, Paul C., Sekaly, Rafick-Pierre, Ross, Colin J., Lavoie, Pascal M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8126652/
https://www.ncbi.nlm.nih.gov/pubmed/34012439
http://dx.doi.org/10.3389/fimmu.2021.655027

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8126652/
https://www.ncbi.nlm.nih.gov/pubmed/34012439
http://dx.doi.org/10.3389/fimmu.2021.655027

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