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Neonatal T Helper 17 Responses Are Skewed Towards an Immunoregulatory Interleukin-22 Phenotype
Newborns are frequently affected by mucocutaneous candidiasis. Th17 cells essentially limit mucosal invasion by commensal Candida spp. Here, we sought to understand the molecular basis for the developmental lack of Th17 cell responses in circulating blood neonatal T cells. Naive cord blood CD4 T cel...
Autores principales: | Razzaghian, Hamid R., Sharafian, Zohreh, Sharma, Ashish A., Boyce, Guilaine K., Lee, Kelsey, Da Silva, Rachel, Orban, Paul C., Sekaly, Rafick-Pierre, Ross, Colin J., Lavoie, Pascal M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8126652/ https://www.ncbi.nlm.nih.gov/pubmed/34012439 http://dx.doi.org/10.3389/fimmu.2021.655027 |
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