Novel Pan-Pim Kinase Inhibitors With Imidazopyridazine and Thiazolidinedione Structure Exert Potent Antitumor Activities

Pim kinases are overexpressed in various types of hematological malignancies and solid carcinomas, and promote cell proliferation and survival. Here in this study, we investigated the preclinical profile of novel pan-Pim kinase inhibitors with imidazopyridazine and thiazolidinedione structure. Imida...

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Detalles Bibliográficos
Autores principales: Sawaguchi, Yuichi, Yamazaki, Ryuta, Nishiyama, Yukiko, Mae, Masayuki, Abe, Atsuhiro, Nishiyama, Hiroyuki, Nishisaka, Fukiko, Ibuki, Tatsuya, Sasai, Toshio, Matsuzaki, Takeshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8126654/
https://www.ncbi.nlm.nih.gov/pubmed/34012401
http://dx.doi.org/10.3389/fphar.2021.672536

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8126654/
https://www.ncbi.nlm.nih.gov/pubmed/34012401
http://dx.doi.org/10.3389/fphar.2021.672536

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