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Structural Profiling of Bacterial Effectors Reveals Enrichment of Host-Interacting Domains and Motifs

Effector proteins are bacterial virulence factors secreted directly into host cells and, through extensive interactions with host proteins, rewire host signaling pathways to the advantage of the pathogen. Despite the crucial role of globular domains as mediators of protein-protein interactions (PPIs...

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Detalles Bibliográficos
Autores principales: Chen, Yangchun Frank, Xia, Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8126662/
https://www.ncbi.nlm.nih.gov/pubmed/34012977
http://dx.doi.org/10.3389/fmolb.2021.626600