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Biomechanical-Based Protocol for in vitro Study of Cartilage Response to Cyclic Loading: A Proof-of-Concept in Knee Osteoarthritis

Osteoarthritis (OA) is an evolving disease and a major cause of pain and impaired mobility. A deeper understanding of cartilage metabolism in response to loading is critical to achieve greater insight into OA mechanisms. While physiological joint loading helps maintain cartilage integrity, reduced o...

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Detalles Bibliográficos
Autores principales: Caravaggi, Paolo, Assirelli, Elisa, Ensini, Andrea, Ortolani, Maurizio, Mariani, Erminia, Leardini, Alberto, Neri, Simona, Belvedere, Claudio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8126668/
https://www.ncbi.nlm.nih.gov/pubmed/34012954
http://dx.doi.org/10.3389/fbioe.2021.634327