Metformin Increases Sarcolemma Integrity and Ameliorates Neuromuscular Deficits in a Murine Model of Duchenne Muscular Dystrophy

Duchenne muscular dystrophy (DMD) is a genetic neuromuscular disease characterized by progressive muscle weakness and wasting. Stimulation of AMP-activated protein kinase (AMPK) has been demonstrated to increase muscle function and protect muscle against damage in dystrophic mice. Metformin is a wid...

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Detalles Bibliográficos
Autores principales: Dong, Xia, Hui, Tiankun, Chen, Jie, Yu, Zheng, Ren, Dongyan, Zou, Suqi, Wang, Shunqi, Fei, Erkang, Jiao, Huifeng, Lai, Xinsheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8126699/
https://www.ncbi.nlm.nih.gov/pubmed/34012406
http://dx.doi.org/10.3389/fphys.2021.642908

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8126699/
https://www.ncbi.nlm.nih.gov/pubmed/34012406
http://dx.doi.org/10.3389/fphys.2021.642908

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