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Clozapine Regulates Microglia and Is Effective in Chronic Experimental Autoimmune Encephalomyelitis

OBJECTIVE: Progressive multiple sclerosis is characterized by chronic inflammation with microglial activation, oxidative stress, accumulation of iron and continuous neurodegeneration with inadequate effectiveness of medications used so far. We now investigated effects of iron on microglia and used t...

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Detalles Bibliográficos
Autores principales: Ceylan, Ulaş, Haupeltshofer, Steffen, Kämper, Laura, Dann, Justus, Ambrosius, Björn, Gold, Ralf, Faissner, Simon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8126707/
https://www.ncbi.nlm.nih.gov/pubmed/34012440
http://dx.doi.org/10.3389/fimmu.2021.656941