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Clozapine Regulates Microglia and Is Effective in Chronic Experimental Autoimmune Encephalomyelitis
OBJECTIVE: Progressive multiple sclerosis is characterized by chronic inflammation with microglial activation, oxidative stress, accumulation of iron and continuous neurodegeneration with inadequate effectiveness of medications used so far. We now investigated effects of iron on microglia and used t...
Autores principales: | Ceylan, Ulaş, Haupeltshofer, Steffen, Kämper, Laura, Dann, Justus, Ambrosius, Björn, Gold, Ralf, Faissner, Simon |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8126707/ https://www.ncbi.nlm.nih.gov/pubmed/34012440 http://dx.doi.org/10.3389/fimmu.2021.656941 |
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