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Transcriptomic response of brain tissue to focused ultrasound‐mediated blood–brain barrier disruption depends strongly on anesthesia

Focused ultrasound (FUS) mediated blood–brain barrier disruption (BBBD) targets the delivery of systemically‐administered therapeutics to the central nervous system. Preclinical investigations of BBBD have been performed on different anesthetic backgrounds; however, the influence of the choice of an...

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Detalles Bibliográficos
Autores principales: Mathew, Alexander S., Gorick, Catherine M., Thim, E. Andrew, Garrison, William J., Klibanov, Alexander L., Miller, G. Wilson, Sheybani, Natasha D., Price, Richard J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8126816/
https://www.ncbi.nlm.nih.gov/pubmed/34027087
http://dx.doi.org/10.1002/btm2.10198