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ICAM-1 induced rearrangements of capsid and genome prime rhinovirus 14 for activation and uncoating

Most rhinoviruses, which are the leading cause of the common cold, utilize intercellular adhesion molecule-1 (ICAM-1) as a receptor to infect cells. To release their genomes, rhinoviruses convert to activated particles that contain pores in the capsid, lack minor capsid protein VP4, and have an alte...

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Detalles Bibliográficos
Autores principales: Hrebík, Dominik, Füzik, Tibor, Gondová, Mária, Šmerdová, Lenka, Adamopoulos, Athanassios, Šedo, Ondrej, Zdráhal, Zbyněk, Plevka, Pavel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8126848/
https://www.ncbi.nlm.nih.gov/pubmed/33947819
http://dx.doi.org/10.1073/pnas.2024251118