Intranasal vaccination with influenza HA/GO-PEI nanoparticles provides immune protection against homo- and heterologous strains

Intranasal (i.n.) immunization is a promising vaccination route for infectious respiratory diseases such as influenza. Recombinant protein vaccines can overcome the safety concerns and long production phase of virus-based influenza vaccines. However, soluble protein vaccines are poorly immunogenic i...

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Detalles Bibliográficos
Autores principales: Dong, Chunhong, Wang, Ye, Gonzalez, Gilbert X., Ma, Yao, Song, Yufeng, Wang, Shelly, Kang, Sang-Moo, Compans, Richard W., Wang, Bao-Zhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2021
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8126854/
https://www.ncbi.nlm.nih.gov/pubmed/33941704
http://dx.doi.org/10.1073/pnas.2024998118

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8126854/
https://www.ncbi.nlm.nih.gov/pubmed/33941704
http://dx.doi.org/10.1073/pnas.2024998118

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