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The aryl hydrocarbon receptor suppresses immunity to oral squamous cell carcinoma through immune checkpoint regulation

Immune checkpoint inhibitors represent some of the most important cancer treatments developed in the last 20 y. However, existing immunotherapy approaches benefit only a minority of patients. Here, we provide evidence that the aryl hydrocarbon receptor (AhR) is a central player in the regulation of...

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Detalles Bibliográficos
Autores principales: Kenison, Jessica E., Wang, Zhongyan, Yang, Kangkang, Snyder, Megan, Quintana, Francisco J., Sherr, David H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8126867/
https://www.ncbi.nlm.nih.gov/pubmed/33941684
http://dx.doi.org/10.1073/pnas.2012692118