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PTENε suppresses tumor metastasis through regulation of filopodia formation

PTEN is one of the most frequently mutated genes in malignancies and acts as a powerful tumor suppressor. Tumorigenesis is involved in multiple and complex processes including initiation, invasion, and metastasis. The complexity of PTEN function is partially attributed to PTEN family members such as...

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Detalles Bibliográficos
Autores principales: Zhang, Qiaoling, Liang, Hui, Zhao, Xuyang, Zheng, Lin, Li, Yunqiao, Gong, Jingjing, Zhu, Yizhang, Jin, Yan, Yin, Yuxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8126949/
https://www.ncbi.nlm.nih.gov/pubmed/33755220
http://dx.doi.org/10.15252/embj.2020105806