Centrosome‐mediated microtubule remodeling during axon formation in human iPSC‐derived neurons

Axon formation critically relies on local microtubule remodeling and marks the first step in establishing neuronal polarity. However, the function of the microtubule‐organizing centrosomes during the onset of axon formation is still under debate. Here, we demonstrate that centrosomes play an essenti...

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Detalles Bibliográficos
Autores principales: Lindhout, Feline W, Portegies, Sybren, Kooistra, Robbelien, Herstel, Lotte J, Stucchi, Riccardo, Hummel, Jessica J A, Scheefhals, Nicky, Katrukha, Eugene A, Altelaar, Maarten, MacGillavry, Harold D, Wierenga, Corette J, Hoogenraad, Casper C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8126955/
https://www.ncbi.nlm.nih.gov/pubmed/33835529
http://dx.doi.org/10.15252/embj.2020106798

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8126955/
https://www.ncbi.nlm.nih.gov/pubmed/33835529
http://dx.doi.org/10.15252/embj.2020106798

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