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Centrosome‐mediated microtubule remodeling during axon formation in human iPSC‐derived neurons
Axon formation critically relies on local microtubule remodeling and marks the first step in establishing neuronal polarity. However, the function of the microtubule‐organizing centrosomes during the onset of axon formation is still under debate. Here, we demonstrate that centrosomes play an essenti...
Autores principales: | Lindhout, Feline W, Portegies, Sybren, Kooistra, Robbelien, Herstel, Lotte J, Stucchi, Riccardo, Hummel, Jessica J A, Scheefhals, Nicky, Katrukha, Eugene A, Altelaar, Maarten, MacGillavry, Harold D, Wierenga, Corette J, Hoogenraad, Casper C |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8126955/ https://www.ncbi.nlm.nih.gov/pubmed/33835529 http://dx.doi.org/10.15252/embj.2020106798 |
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