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TRIM37 prevents formation of condensate-organized ectopic spindle poles to ensure mitotic fidelity

Centrosomes are composed of a centriolar core surrounded by pericentriolar material that nucleates microtubules. The ubiquitin ligase TRIM37 localizes to centrosomes, but its centrosomal roles are not yet defined. We show that TRIM37 does not control centriole duplication, structure, or the ability...

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Detalles Bibliográficos
Autores principales: Meitinger, Franz, Kong, Dong, Ohta, Midori, Desai, Arshad, Oegema, Karen, Loncarek, Jadranka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8127006/
https://www.ncbi.nlm.nih.gov/pubmed/33983387
http://dx.doi.org/10.1083/jcb.202010180