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USP19 promotes hypoxia-induced mitochondrial division via FUNDC1 at ER-mitochondria contact sites

The ER tethers tightly to mitochondria and the mitochondrial protein FUNDC1 recruits Drp1 to ER-mitochondria contact sites, subsequently facilitating mitochondrial fission and preventing mitochondria from undergoing hypoxic stress. However, the mechanisms by which the ER modulates hypoxia-induced mi...

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Detalles Bibliográficos
Autores principales: Chai, Peiyuan, Cheng, Yiru, Hou, Chuyi, Yin, Lei, Zhang, Donghui, Hu, Yingchun, Chen, Qingzhou, Zheng, Pengli, Teng, Junlin, Chen, Jianguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8127008/
https://www.ncbi.nlm.nih.gov/pubmed/33978709
http://dx.doi.org/10.1083/jcb.202010006