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Non-toxic sulfur inhibits LPS-induced inflammation by regulating TLR-4 and JAK2/STAT3 through IL-6 signaling

Janus kinase 2 (JAK2) and STAT3 signaling is considered a major pathway in lipopolysaccharide (LPS)-induced inflammation. Toll-like receptor 4 (TLR-4) is an inflammatory response receptor that activates JAK2 during inflammation. STAT3 is a transcription factor for the pro-inflammatory cytokine IL-6...

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Detalles Bibliográficos
Autores principales: Kang, Dong Young, Sp, Nipin, Jo, Eun Seong, Rugamba, Alexis, Kim, Hyoung Do, Kim, Il Ho, Park, Jong-Chan, Bae, Se Won, Jang, Kyoung-Jin, Yang, Young Mok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8127030/
https://www.ncbi.nlm.nih.gov/pubmed/33907855
http://dx.doi.org/10.3892/mmr.2021.12124