Cargando…

Rapamycin protects against aristolochic acid nephropathy in mice by potentiating mammalian target of rapamycin-mediated autophagy

Autophagy serves a crucial role in the etiology of kidney diseases, including drug-induced renal impairment, inherited kidney disease, diabetic nephropathy and aristolochic acid nephropathy (AAN) and is, therefore, a potential target for treatment. We previously demonstrated that rapamycin could att...

Descripción completa

Detalles Bibliográficos
Autores principales: Lin, Fan, Liu, Yunqi, Tang, Lili, Xu, Xiaohui, Zhang, Xueli, Song, Yifan, Chen, Bicheng, Ren, Yeping, Yang, Xiangdong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8127069/
https://www.ncbi.nlm.nih.gov/pubmed/33955513
http://dx.doi.org/10.3892/mmr.2021.12134