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Rapamycin protects against aristolochic acid nephropathy in mice by potentiating mammalian target of rapamycin-mediated autophagy
Autophagy serves a crucial role in the etiology of kidney diseases, including drug-induced renal impairment, inherited kidney disease, diabetic nephropathy and aristolochic acid nephropathy (AAN) and is, therefore, a potential target for treatment. We previously demonstrated that rapamycin could att...
Autores principales: | Lin, Fan, Liu, Yunqi, Tang, Lili, Xu, Xiaohui, Zhang, Xueli, Song, Yifan, Chen, Bicheng, Ren, Yeping, Yang, Xiangdong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8127069/ https://www.ncbi.nlm.nih.gov/pubmed/33955513 http://dx.doi.org/10.3892/mmr.2021.12134 |
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