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treeclimbR pinpoints the data-dependent resolution of hierarchical hypotheses

treeclimbR is for analyzing hierarchical trees of entities, such as phylogenies or cell types, at different resolutions. It proposes multiple candidates that capture the latent signal and pinpoints branches or leaves that contain features of interest, in a data-driven way. It outperforms currently a...

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Detalles Bibliográficos
Autores principales: Huang, Ruizhu, Soneson, Charlotte, Germain, Pierre-Luc, Schmidt, Thomas S.B., Mering, Christian Von, Robinson, Mark D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8127214/
https://www.ncbi.nlm.nih.gov/pubmed/34001188
http://dx.doi.org/10.1186/s13059-021-02368-1