Cargando…
Design considerations of an IL13Rα2 antibody–drug conjugate for diffuse intrinsic pontine glioma
Diffuse intrinsic pontine glioma (DIPG), a rare pediatric brain tumor, afflicts approximately 350 new patients each year in the United States. DIPG is noted for its lethality, as fewer than 1% of patients survive to five years. Multiple clinical trials involving chemotherapy, radiotherapy, and/or ta...
Autores principales: | , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8127302/ https://www.ncbi.nlm.nih.gov/pubmed/34001278 http://dx.doi.org/10.1186/s40478-021-01184-9 |