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On the relation of gene essentiality to intron structure: a computational and deep learning approach
Essential genes have been studied by copy number variants and deletions, both associated with introns. The premise of our work is that introns of essential genes have distinct characteristic properties. We provide support for this by training a deep learning model and demonstrating that introns alon...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Life Science Alliance LLC
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8127325/ https://www.ncbi.nlm.nih.gov/pubmed/33906938 http://dx.doi.org/10.26508/lsa.202000951 |