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On the relation of gene essentiality to intron structure: a computational and deep learning approach

Essential genes have been studied by copy number variants and deletions, both associated with introns. The premise of our work is that introns of essential genes have distinct characteristic properties. We provide support for this by training a deep learning model and demonstrating that introns alon...

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Detalles Bibliográficos
Autores principales: Schonfeld, Ethan, Vendrow, Edward, Vendrow, Joshua, Schonfeld, Elan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8127325/
https://www.ncbi.nlm.nih.gov/pubmed/33906938
http://dx.doi.org/10.26508/lsa.202000951

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