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Cathepsin K maintains the compartment of bone marrow T lymphocytes in vivo

In this study, we investigated the influence of the loss of cathepsin K (Ctsk) gene on the hematopoietic system in vitro and in vivo. We found that cultures with lineage(−) SCA1(+) KIT(+) (LSK) cells on Ctsk deficient stromal cells display reduced colony formation and proliferation, with increased d...

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Detalles Bibliográficos
Autores principales: Hausinger, Renate, Hackl, Marianne, Jardon Alvarez, Ana, Kehr, Miriam, Romero Marquez, Sandra, Hettler, Franziska, Kehr, Christian, Grziwok, Sandra, Schreck, Christina, Peschel, Christian, Istvánffy, Rouzanna, Oostendorp, Robert A. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8127559/
https://www.ncbi.nlm.nih.gov/pubmed/33592138
http://dx.doi.org/10.1002/iid3.412