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Cathepsin K maintains the compartment of bone marrow T lymphocytes in vivo
In this study, we investigated the influence of the loss of cathepsin K (Ctsk) gene on the hematopoietic system in vitro and in vivo. We found that cultures with lineage(−) SCA1(+) KIT(+) (LSK) cells on Ctsk deficient stromal cells display reduced colony formation and proliferation, with increased d...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8127559/ https://www.ncbi.nlm.nih.gov/pubmed/33592138 http://dx.doi.org/10.1002/iid3.412 |