Functional analysis of XRCC4 mutations in reported microcephaly and growth defect patients in terms of radiosensitivity

Non-homologous end joining is one of the main pathways for DNA double-strand break (DSB) repair and is also implicated in V(D)J recombination in immune system. Therefore, mutations in non-homologous end-joining (NHEJ) proteins were found to be associated with immunodeficiency in human as well as in...

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Detalles Bibliográficos
Autores principales: Asa, Anie Day D C, Wanotayan, Rujira, Sharma, Mukesh Kumar, Tsukada, Kaima, Shimada, Mikio, Matsumoto, Yoshihisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Fundamental Radiation Science
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8127669/
https://www.ncbi.nlm.nih.gov/pubmed/33842963
http://dx.doi.org/10.1093/jrr/rrab016

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8127669/
https://www.ncbi.nlm.nih.gov/pubmed/33842963
http://dx.doi.org/10.1093/jrr/rrab016

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