Oxidative stress induces cell death partially by decreasing both mRNA and protein levels of nicotinamide phosphoribosyltransferase in differentiated PC12 cells

BACKGROUND. Multiple studies have indicated crucial roles of NAD(+) deficiency in several neurological diseases and aging. It is critical to discover the mechanisms underlying the NAD(+) deficiency. A decreased level of Nicotinamide phosphoribosyltransferase (Nampt)—an important enzyme in the salvag...

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Detalles Bibliográficos
Autores principales: Zhou, Cuiyan, Ying, Weihai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2021
Materias:
Biochemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8127959/
https://www.ncbi.nlm.nih.gov/pubmed/34040894
http://dx.doi.org/10.7717/peerj.11401

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8127959/
https://www.ncbi.nlm.nih.gov/pubmed/34040894
http://dx.doi.org/10.7717/peerj.11401

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