DZNep, an inhibitor of the histone methyltransferase EZH2, suppresses hepatic fibrosis through regulating miR-199a-5p/SOCS7 pathway

BACKGROUND: Hepatic fibrosis is a common response to chronic liver injury. Recently, the role of DZNep (a histone methyltransferase EZH2 inhibitor) in repressing pulmonary and renal fibrosis was verified. However, the potential effect of DZNep on hepatic fibrosis has not been elucidated. METHODS: Th...

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Detalles Bibliográficos
Autores principales: Ding, Rongrong, Zheng, Jianming, Li, Ning, Cheng, Qi, Zhu, Mengqi, Wang, Yanbing, Zhou, Xinlan, Zhang, Zhanqing, Shi, Guangfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2021
Materias:
Biochemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8127960/
https://www.ncbi.nlm.nih.gov/pubmed/34040893
http://dx.doi.org/10.7717/peerj.11374

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8127960/
https://www.ncbi.nlm.nih.gov/pubmed/34040893
http://dx.doi.org/10.7717/peerj.11374

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