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Fidelity of base-pair recognition by a 3′–5′ polymerase: mechanism of the Saccharomyces cerevisiae tRNA(His) guanylyltransferase

The tRNA(His) guanylyltransferase (Thg1) was originally discovered in Saccharomyces cerevisiae where it catalyzes 3′–5′ addition of a single nontemplated guanosine (G(−1)) to the 5′ end of tRNA(His). In addition to this activity, S. cerevisiae Thg1 (SceThg1) also catalyzes 3′–5′ polymerization of Wa...

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Detalles Bibliográficos
Autores principales: Patel, Krishna J., Yourik, Paul, Jackman, Jane E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8127993/
https://www.ncbi.nlm.nih.gov/pubmed/33790044
http://dx.doi.org/10.1261/rna.078686.121