Long Non-coding RNA MEG3 Promotes Renal Tubular Epithelial Cell Pyroptosis by Regulating the miR-18a-3p/GSDMD Pathway in Lipopolysaccharide-Induced Acute Kidney Injury

Background and Objective: Acute kidney injury (AKI) is a complication of sepsis. Pyroptosis of gasdermin D (GSDMD)-mediated tubular epithelial cells (TECs) play important roles in pathogenesis of sepsis-associated AKI. Long non-coding RNA (lncRNA) maternally expressed gene 3 (MEG3), an imprinted gen...

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Detalles Bibliográficos
Autores principales: Deng, Junhui, Tan, Wei, Luo, Qinglin, Lin, Lirong, Zheng, Luquan, Yang, Jurong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8128073/
https://www.ncbi.nlm.nih.gov/pubmed/34012408
http://dx.doi.org/10.3389/fphys.2021.663216

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8128073/
https://www.ncbi.nlm.nih.gov/pubmed/34012408
http://dx.doi.org/10.3389/fphys.2021.663216

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