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HDAC2 links ubiquitination to tumor suppression in synovial sarcoma
The function of histone deacetylase 2 (HDAC2) in transcriptional regulation and its role in oncogenesis have been well established. Here we discuss a transcription-independent HDAC2 pathway controlling cancer-related protein stability via the mouse double minute 2 homolog (MDM2) ubiquitin ligase. In...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Taylor & Francis
2021
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8128193/ https://www.ncbi.nlm.nih.gov/pubmed/34027048 http://dx.doi.org/10.1080/23723556.2021.1914291 |